The Essential Amino Acids The essential amino acids are arginine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine. These amino acids are required in the diet Alpha-ketoglutarate: Alpha-ketoglutarate is the keto acid produced by deamination of glutamate. It is a key intermediate in the Krebs cycle, coming after isocitrate and before succinyl CoA. Anaplerotic reactions, or supplementation, can replenish this cycle increasing energy and stamina. Alphaketoglutarate is one of the most important nitrogen transporters in metabolic pathways. The amino groups of amino acids are attached to it by transamination and carried to the liver where the urea cycle takes place. Alpha-ketoglutarate is transaminated, along with glutamine, to form the excitatory neurotransmitter glutamate. Glutamate can then be decarboxylated, via glutamic acid decarboxylase, requiring vitamin B6 (in the form of pyridoxyl-5-phosphate, known as P5P) into the inhibitory neurotransmitter GABA. Adequate P5P was included in this formula to facilitate such conversions efficiently.
Arginine: Arginine is a complex amino acid that is often found at the active (or catalytic) site in proteins and enzymes due to its amine-containing side chain. Arginine plays an important role in cell division, the healing of wounds, removing ammonia from the body, immune function, release of hormones and the production of nitric oxide. Histidine: Histidine is the direct precursor of histamine and is needed to help grow and repair body tissues and to maintain the myelin sheaths that protect nerve cells. It also helps manufacture red and white blood cells and helps to protect the body from heavy metal toxicity. Histamine also stimulates the secretion of the digestive enzyme, gastrin. Isoleucine: Isoleucine belongs to a special group of amino acids called branched-chain amino acids (BCAAs), which are needed to help maintain and repair muscle tissue. Leucine and valine are the other two branched-chain amino acids. Isoleucine is needed for hemoglobin formation and also helps to maintain regular energy levels. Isoleucine is also important for stabilizing and regulating blood sugar and energy levels. Leucine: Leucine is also a member of the branched-chain amino acid family along with valine and isoleucine. The branched-chain amino acids (BCAAs) are found in proteins of all life forms. Leucine ties glycine for the position of second most common amino acid found in proteins. Leucine is necessary for the optimal growth of infants and for proper nitrogen balance in adults. Lysine: Lysine is an essential amino acid which is a major building block for all protein and is needed for proper growth and bone development in children. Lysine helps the body absorb and conserve calcium and it plays an important role in the formation of collagen. The lysine in this formula may help prevent some common viral outbreaks, such as cold sores caused by herpes viruses. Methionine: Methionine is an important amino acid that helps to initiate translation of messenger RNA by being the first amino acid incorporated into the N-terminal position of all proteins. Methionine supplies sulfur and other compounds required by the body for normal metabolism, detoxification and growth. Methionine reacts with adenosine triphosphate to form S-adenosyl methionine. S-adenosyl methionine is the principal methyl donor in the body and contributes to the synthesis of many important substances, including epinephrine and choline.
% Daily Value Phenylalanine: Phenylalanine is an essential amino acid that plays a key role in the biosynthesis of other amino acids and various neurotransmitters. Threonine: Threonine is an alcohol-containing essential amino acid that is an important component in the formation of protein, collagen, elastin and tooth enamel. It is also important for production of neurotransmitters and health of the nervous system. Valine: Valine is a branched-chain amino acid (BCAA) that is closely related to leucine and isoleucine both in structure and function. Valine is a constituent of fibrous protein in the body and has been found useful in muscle health, and the improvement of mental and emotional disorders, insomnia and nervousness. Valine may also help treat malnutrition associated with drug addiction. * Tryptophan was not included in Amino Acid Essentials in order to give the health care practitioner the ability to use this supplement regardless of the patient's serotonin-related status and to allow the practitioner to add tryptophan Who should take Amino Essentials? Amino Acid Essentials is useful as a general supplement to diets that are insufficient in quality protein, for athletes that require additional amino acids to maintain or achieve greater lean body mass, for patients who are cachexic from chronic illness or GI malabsorption, for individuals who are in catabolic states due to stress or illness, for those recovering from surgery or tissue trauma, for people wanting better quality hair and nails and for people who have been found to have confirmed amino acid deficiencies on metabolic testing.
How should Amino Essentials be taken? 2 capsules, twice daily (4 capsules) will deliver 3 grams of free-form essential amino acids and is the suggested dose for standard applications. More aggressive dosing can be used in cases where the significant addition of muscle mass is desired and also in confirmed amino acid deficiency states. STORE IN A COOL, DRY PLACE. KEEP OUT OF REACH OF CHILDREN. This product does not contain wheat, yeast, soy protein, gluten, eggs, dairy, corn, artificial colors, flavors, sugars, or preservatives. THIS INFORMATION IS PROVIDED FOR THE USE OF PHYSICIANS AND OTHER LICENSED HEALTH CARE PRACTITIONERS ONLY. THIS INFORMATION IS INTENDED FOR PHYSICIANS AND OTHER LICENSED HEALTH CARE PROVIDERS TO USE AS A BASIS FOR DETERMINING WHETHER OR NOT TO RECOMMEND THESE PRODUCTS TO THEIR PATIENTS. THIS MEDICAL AND SCIENTIFIC INFORMATION IS NOT FOR USE BY CONSUMERS. THE DIETARY SUPPLEMENT PRODUCTS OFFERED BY SPORTS NUTRITION LABS ARE NOT INTENDED FOR USE BY CONSUMERS AS A MEANS TO CURE, TREAT, PREVENT, DIAGNOSE, OR MITIGATE ANY DISEASE OR OTHER MEDICAL CONDITION.
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